Pregnancy Home > Clomid Warnings and Precautions

Women who have ovarian cysts, uncontrolled thyroid problems, or liver disease should not take Clomid. Women who are pregnant should also avoid taking the medication. Other Clomid warnings and precautions include telling your healthcare provider if you are breastfeeding; seeking medical attention immediately if you develop any symptoms of ovarian hyperstimulation syndrome; and being aware that the medicine can increase the chance of multiple births (twins, triplets, or more).

Clomid: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Clomid® (clomiphene citrate) if you have:
  • Thyroid or adrenal problems
  • A brain tumor
  • Ovarian cysts
  • Polycystic ovarian syndrome (PCOS)
  • Fibroids
  • Depression
  • Liver disease, including liver failure or cirrhosis
  • Abnormal menstrual bleeding (abnormal periods)
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
  • Are pregnant or may be pregnant
  • Are breastfeeding.
Also, tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Some Clomid Precautions and Warnings

Some warnings and precautions to be aware of with this drug include:
  • Clomid is considered a pregnancy Category X medicine. This means that it is likely to cause harm to an unborn baby. Do not use Clomid if you are or might be pregnant (see Clomid and Pregnancy for more information).
  • It is not known if Clomid is passed through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, be sure to talk with your healthcare provider about this.
  • Clomid can cause vision changes, including blurred vision or seeing spots. Be aware that these visions changes could affect your ability to drive or operate heavy machinery.
  • Ovarian hyperstimulation syndrome (OHSS) can occur with Clomid. OHSS is characterized by enlarged ovaries and can be extremely dangerous. In severe cases, the ovaries could rupture. Symptoms of OHSS include abdominal (or stomach) pain or enlargement, upset stomach (nausea), vomiting, diarrhea, and weight gain. If you have these symptoms, contact your healthcare provider right away.
  • Taking Clomid increases your risk of multiple pregnancies, including twins, triplets, or more (see Clomid and Twins).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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