Pregnancy Home > Clomid and Pregnancy

While Clomid is a medication that helps women become pregnant, it is not safe to use if you already are pregnant. During animal studies on Clomid and pregnancy, the medicine was shown to cause birth defects to the developing fetus. The U.S. Food and Drug Administration has classified Clomid as a pregnancy Category X medicine, meaning it should not be used during pregnancy.

Is Clomid Safe During Pregnancy? -- An Overview

For women who are pregnant or might be pregnant, Clomid® (clomiphene citrate) is very dangerous. This is based on animal studies that looked at the effects of Clomid during pregnancy. Clomid has been given a pregnancy Category X classification based on its risks to the unborn fetus.

Clomid and Pregnancy Category X

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category X is given to medicines that show problems to the fetus in animal studies or in humans who have mistakenly taken the medicine.
Because it would be unethical to give Clomid to pregnant women, the use of Clomid in pregnant women has never been studied in a clinical trial. However, based on animal studies, we know about the problems that Clomid may potentially cause. The use of a pregnancy Category X medicine during pregnancy is not recommended.
Your healthcare provider should make sure you are not already pregnant before you start Clomid.

Recommendations on Clomid and Pregnancy

First of all, Clomid is used to help women get pregnant, so there is no reason for a pregnant woman to intentionally take Clomid. Secondly, taking Clomid during pregnancy can cause birth defects. Therefore, if you are pregnant or think you may already be pregnant, let your healthcare provider know immediately. You should not take Clomid if you are or may be pregnant. Your healthcare provider should make sure you are not pregnant before you start Clomid.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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