Pregnancy Home > Cervidil Side Effects

There are some potentially serious problems Cervidil may cause, such as low blood pressure, abnormally strong uterine contractions, and persistent vomiting. Although these types of problems may require medical treatment, most reactions to this drug tend to be minor and easy to treat. Some of the more common side effects of Cervidil include fetal distress and frequent uterine contractions.

An Introduction to Cervidil Side Effects

Just like any medicine, Cervidil® (dinoprostone vaginal insert) can cause side effects. However, not everyone who receives the drug will have problems. In fact, most women tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Cervidil. Your healthcare provider can discuss a more complete list with you.)
 

Common Side Effects of Cervidil

Cervidil has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people given Cervidil were documented and then compared to the side effects that occurred in a similar group of people given a placebo (a vaginal insert that did not contain any active ingredients).
 
In these studies, the most common Cervidil side effects included:
 
  • Very strong or frequent uterine contractions -- in up to 4.7 percent of women
  • Signs that the fetus is not well or is fatigued (fetal distress) -- up to 3.8 percent
  • Both very strong or frequent uterine contractions and fetal distress -- up to 2.9 percent.
 
Rare side effects, occurring in less than 1 percent of women, included:
 
  • Fever
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal (stomach) pain.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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