For most women, prescription prenatal vitamins are probably not significantly better than a good non-prescription prenatal vitamin. However, for women who have insurance or Medicaid, a prescription prenatal vitamin may be preferred, as some (or all) of the cost may be covered by the insurance or Medicaid. Some of the newer prescription prenatal vitamins are rather expensive (some cost more than a dollar a day), although generic prescription prenatal vitamins are generally very affordable.