Makena^TM (hydroxyprogesterone caproate) is the first and only drug approved by the United States Food and Drug Administration for the prevention of preterm birth. It is given as a weekly injection that is started between weeks 16 and 21 of pregnancy. The medication is only approved for use in women who have a history of giving birth too soon.

This medicine is not appropriate for everyone; your healthcare provider needs up-to-date information on your medical history and what medicines you are taking before prescribing Makena. For example, talk to your healthcare provider if you have depression, diabetes, asthma, or migraines. Some of the most common side effects include hives, pain at the injection site, and itching.

(For more information on this drug, click Makena. This full-length article goes into greater detail about what to expect during treatment, other potential side effects, and more.)

Makena Drug Information

List of references (click here)

Written by/reviewed by: Arthur Schoenstadt, MD

Last reviewed by: Arthur Schoenstadt, MD

Makena Drug Interactions

Makena Warnings and Precautions

Makena Overdose

Makena and Pregnancy

Makena and Breastfeeding

Generic Makena

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