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PreferaOB Drug Interactions
Because a number of drugs can cause interactions with PreferaOB, make sure your healthcare provider has a current list of all medications that you are taking. Advil, Cipro, and Bayer are just a few of the medicines that may negatively react with PreferaOB. Some of these reactions may decrease the effectiveness of the medications or increase your risk for side effects.
PreferaOB® may react with a number of other products. Some of the drugs that can interact with PreferaOB include but are not limited to:
- Bisphosphonates, such as:
- Alendronate (Fosamax®, Fosamax Plus D®)
- Etidronate (Didronel®)
- Ibandronate (Boniva®)
- Pamidronate (Aredia®)
- Risedronate (Actonel®, Actonel With Calcium®)
- Tiludronate (Skelid®)
- Zoledronic acid (Reclast®, Zometa®)
- Fluoroquinolone antibiotics, such as:
- Ciprofloxacin (Cipro®, Cipro® XR, Proquin® XR)
- Gatifloxacin (Tequin®)
- Levofloxacin (Levaquin®)
- Moxifloxacin (Avelox®)
- Norfloxacin (Noroxin®)
- Ofloxacin (Floxin®)
- Medications that "thin" the blood, such as anticoagulant and antiplatelet drugs, including:
- Antithrombin (ATryn®, Thrombate III®)
- Argatroban
- Aspirin (Bayer® and others)
- Bivalirudin (Angiomax®)
- Cilostazol (Pletal®)
- Clopidogrel (Plavix®)
- Dabigatran (Pradaxa®)
- Dipyridamole (Persantine®)
- Drotrecogin alfa (Xigris®)
- Eptifibatide (Integrilin®)
- Fondaparinux (Arixtra®)
- Heparin or heparin-like products, including dalteparin (Fragmin®), enoxaparin (Lovenox®), or tinzaparin (Innohep®)
- Lepirudin (Refludan®)
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
- Celecoxib (Celebrex®)
- Diclofenac (Cambia™, Cataflam®, Flector®, Solaraze® Gel, Voltaren®, Voltaren® Gel, Voltaren®-XR, Voltaren Ophthalmic®, Zipsor®)
- Etodolac (Lodine®, Lodine® XL)
- Ibuprofen (Motrin®, Advil®, Nuprin®)
- Indomethacin (Indocin®, Indocin SR®)
- Ketoprofen (Orudis®, Actron®, Oruvail®)
- Ketorolac (Toradol®)
- Meloxicam (Mobic®)
- Nabumetone (Relafen®)
- Naproxen (Naprosyn®) or naproxen sodium (Aleve®, Anaprox®, Naprelan®)
- Oxaprozin (Daypro®)
- Piroxicam (Feldene®)
- Others (see List of NSAIDs for a more complete list of these medications)
- Rivaroxaban (Xarelto®)
- Thrombolytics, such as:
- Alteplase (Activase®)
- Reteplase (Retavase®)
- Streptokinase (Streptase®)
- Tenecteplase (TNKase®)
- Orlistat (Alli®, Xenical®)
- Sucralfate (Carafate®)
- Tetracycline antibiotics, such as:
- Demeclocycline (Declomycin®)
- Doxycycline (Adoxa®, Alodox®, Atridox®, Doryx®, Monodox®, NutriDox™, Oracea®, Periostat®, Vibra-Tabs®, Vibramycin®)
- Minocycline (Arestin®, Cleeravue-M®, Dynacin®, Minocin®, Myrac™, Solodyn®)
- Tetracycline (Sumycin®)
- Thyroid medications, such as:
- Liothyronine (Cytomel®)
- Liotrix (Thyrolar®)
- Levothyroxine (Levothroid®, Levoxyl®, Synthroid®, Tirosint®, Unithroid®)
- Thyroid (Armor® Thyroid, Nature-Throid®, Westhroid®).
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD



