Makena Dosage

In most cases, Makena is injected once every seven days. This medication is designed to be injected into a muscle in the upper-outer area of the buttocks, and should be injected by a healthcare provider. Makena dosing is usually started between 16 and 21 weeks of pregnancy and is continued up to 37 weeks of pregnancy or until delivery, whichever comes first.

An Introduction to Your Dosage of Makena

There is only one standard dose for Makena™ (hydroxyprogesterone caproate), regardless of your age or weight, although there is some variability as to when exactly in pregnancy the drug is started.
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Makena Dosing Guidelines

The usual recommended dosage of Makena is 250 mg (1 mL) injected into a muscle (intramuscularly) once every seven days. It is usually started between 16 and 21 weeks of pregnancy and continued to 37 weeks of pregnancy (up to 36 weeks, 6 days) or until delivery, whichever is first.
Each vial of Makena contains five doses (5 mL). The entire vial must be used within five weeks, which is not a problem if you stay on track with your injections.

General Information on Using Makena

Some considerations for women to keep in mind when receiving Makena include the following:
  • This medication comes as an injection. It is injected by a healthcare provider once a week (once every seven days). Makena is not intended for self-injection.
  • The injections are given in the upper-outer area of the buttocks, near the hip.
  • For the medication to work properly, it must be given as prescribed.
  • If you are unsure about anything related to your Makena dosage, please talk with your healthcare provider, nurse, or pharmacist.
Pregnancy and Pain

Makena Drug Information

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