Pregnancy Home > Folic Acid Drug Interactions
Certain medications may cause problems if taken together with folic acid. Drug interactions may occur if folic acid is taken in combination with methotrexate, phenytoin, or pyrimethamine. Folic acid could potentially decrease the effectiveness of these medications. To help minimize the risk of developing drug interactions with folic acid, be sure to talk to your healthcare provider if you are taking any other medicines.
- Methotrexate (Rheumatrex®, Trexall®)
- Phenytoin (Dilantin®, Phenytek®) or fosphenytoin (Cerebyx®)
- Pyrimethamine (Daraprim®).