Folic acid may decrease the effectiveness of pyrimethamine for treating certain parasitic infections. This does not seem to be a problem when treating malaria, though. Check with your healthcare provider before combining pyrimethamine with a folic acid supplement.
Final Thoughts on Folic Acid Drug Interactions
It is possible that not every drug interaction with folic acid was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the folic acid interactions that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Jellin JM, editor. Pharmacist's Letter/Prescriber's Letter Natural Medicines Comprehensive Database Web site. Available at: http://naturaldatabase.com/. Accessed January 25, 2008.
National Institutes of Health. Office of Dietary Supplements. Dietary supplement fact sheet: folate (8/22/2005). NIH Web site. Available at: http://ods.od.nih.gov/factsheets/folate.asp. Accessed January 25, 2008.
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