Available in the form of a vaginal insert, Cervidil® (dinoprostone vaginal insert) is placed high in the vagina, near the cervix. It is approved for use in women who are close to delivery and have a medical reason to begin inducing labor.
The Cervidil vaginal insert is administered by a healthcare provider in a hospital setting. You must be lying down when the product is inserted, and you must remain lying down for at least two hours to make sure the insert stays in place. It is left in place until active labor begins, but for no more than 12 hours.
This prescription medication contains a manufactured (synthetic) version of a hormone found naturally in the body. It works by relaxing and softening the cervix ("ripening"), which allows the cervix to dilate to allow the baby to pass through the birth canal.
(For more information, click Cervidil. This article contains more information on how this drug works, dosing guidelines, possible side effects, and more.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Cervidil [package insert]. St. Louis, MO: Forest Pharmaceuticals, Inc.;2010 April.
Cervidil Web site. Available at: http://www.cervidil.com/. Accessed January 23, 2012.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed January 23, 2012.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed January 23, 2012.
Dinoprostone. Drug Facts and Comparisons. Drug Facts and Comparisons 4.0 [online]. 2012. Available from Wolters Kluwer Health, Inc. Accessed January 24, 2012.
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