Diclegis and Breastfeeding

Research suggests that Diclegis (doxylamine and pyridoxine) does pass through breast milk in women. Drowsiness is the main side effect of this drug, so if your healthcare provider recommends using it while nursing, make sure to monitor your child for drowsiness or significant sedation. The manufacturer of the drug recommends that breastfeeding women not take Diclegis.

Can Breastfeeding Women Take Diclegis?

Diclegis® (doxylamine and pyridoxine) is expected to pass through breast milk in humans. The manufacturer of Diclegis recommends that it should not be used in breastfeeding women. Therefore, if you are breastfeeding, talk with your healthcare provider before taking Diclegis.

More Information on Diclegis and Breastfeeding

Diclegis is a combination medication. It contains doxylamine (an antihistamine) and pyridoxine (vitamin B6). Pyridoxine is known to pass through breast milk, and does not cause any problems in nursing infants.
Based on the properties of doxylamine, it is also thought to pass through breast milk. However, the effects of the medication during breastfeeding have not been studied. Therefore, it is not entirely known whether doxylamine would cause any problems in a breastfed infant. Excitement, irritability, and sedation have been reported in infants exposed to doxylamine through breast milk.
The main side effect of Diclegis is drowsiness, and there is a possibility that the drug could cause significant sedation in a nursing child. This side effect may be particularly problematic in infants who have sleep apnea or other breathing problems.
Diclegis is approved to treat nausea and vomiting during pregnancy. Therefore, its use in a breastfeeding woman would be considered an "off-label" (unapproved) use. If your healthcare provider recommends using Diclegis while you are breastfeeding, make sure to watch your infant for possible sedation or drowsiness, which could be caused by the medication.
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Diclegis Medication Information

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