Does Clomid Cause Migraines?
Several side effects are possible with
Clomid® (
clomiphene citrate), and
migraines may be one of them. This data comes from clinical trials in which the drug was studied extensively and side effects were documented.
Clomid and Migraines: Understanding Clinical Trials
Before medicines are approved, they must go through several clinical studies, where thousands of people are given a particular medicine and are then compared to a group of people who were not given the medicine.
In these studies, side effects are always documented. As a result, it is possible to see which side effects occur, how often they appear, and how they compare to the group not taking the medicine. Side effects are then usually separated into those side effects that occur in more than 1 percent of people (common side effects) and those that occur in less than 1 percent of people (rare side effects).
Headaches (including migraines) were reported in up to 1.3 percent of women taking Clomid. These studies did not separate
migraine headaches from other
types of headaches. They also did not report how many women who did not take Clomid had headaches. Therefore, it is difficult to say the effects of Clomid on migraine headaches. It is also difficult to know whether women with a history of migraines are at increased risk for them during Clomid therapy.